Neroli oil is very relaxing & helps in providing relief from chronic anxiety, depression, fear, shock & stress. It also has a calming effect and can be beneficial to digestive tract. It can also be used for intestinal spasms, colitis & diarrhea. It helps insomnia, and as it has sedative effects, it is also useful for treating depression, anxiety & shock as well as calming heart palpitations, treating headaches, neuralgia & vertigo. C. aurantium is also used for the treatment of several ailments such as anxiety, lung and prostate cancers, and gastrointestinal disorders and obesity. Due to the prohibition of Ephedra sinica Stapf. in Farw.-containing weight loss products in the market, C. aurantium has found an important place as a preferable agent to replace ephedra, as it contains p-synephrine, a phenylethanolamine type alkaloid, which is chemically similar to adrenergic agents, as appetite suppressants. C. aurantium possesses multiple therapeutic potentials. These biological credentials include anticancer, antianxiety, antiobesity, antibacterial, antioxidant, pesticidal, and antidiabetic activities. The essential oil of C. aurantium was reported to display marked pharmacological effects and great variation in chemical composition depending on growing locations but mostly contained limonene, linalool, and β-myrcene. Phytochemically, C. aurantium is rich in p-synephrine, an alkaloid, and many health-giving secondary metabolites such as flavonoids.